
Isla Santa María Vacations from $496
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Your Isla Santa María Vacation
Amazing adventures await when you reserve a vacation package to Isla Santa María. Whether you're a foodie, history buff or just a traveler who loves to experience new places, there's something for everyone in this lively city. Post Office Bay is one of the top attractions to include on your sightseeing agenda during a trip to Isla Santa María. Expedia is here to help you escape the everyday. Tailor your vacation to Isla Santa María to suit your travel style, whatever that may be.
The Latest Isla Santa María vacation packages


Mi Playa Galapagos Beachfront
Reviewed on May 11, 2023


Royal Palm Galapagos, Curio Collection Hotel by Hilton
Reviewed on Apr 20, 2025

Discover the most popular places to visit in Isla Santa María

Post Office Bay
Commune with nature and explore the great outdoors at Post Office Bay during your travels in Isla Santa María. While you're in the area, wander around the natural setting.

Punta Suarez
Explore the great outdoors at Punta Suarez, a lovely green space in Isla Santa María. Wander the seaside and white-sand beaches while you're in the area.
What to do in Isla Santa María

Full Day Santa Fe & " Playa escondida" snorkeling tour
Isla Santa María Hotel Deals

Hotel Fiesta
Reviewed on Aug 6, 2025

Hotel el descanso del Guia
Reviewed on Jun 29, 2025

Finch Bay Galapagos Hotel
Reviewed on Dec 31, 2024